2013 Publications (27)

  • Biotransformation of Silybin and its Congeners

    V. Křen, P. Marhol, K. Purchartová, E. Gabrielová and M. Modrianský

    Current Drug Metabolism, 2013, 14 (10), 1009-1021

  • Effect of 3-O-Galloyl Substitution on the Electrochemical Oxidation of Quercetin and Silybin Galloyl Esters at Glassy Carbon Electrode

    M. Zatloukalová, T. Adrian Enache, V. Křen, J. Ulrichová, Jan Vacek, A. M. Oliveira-Brett

    Electroanalysis, 2013, 25, No. 7, 1621 – 1627

  • Recombinant a-L-rhamnosidase of Aspergillus terreus immobilization in polyvinylalcohol hydrogel and its application in rutin derhamnosylation

    M. Rebroš, A. Pilniková, D. Šimčíková, L. Weignerová, R. Stloukal, V. Křen & M. Rosenberg

    Biocatalysis and Biotransformation, 2013, 31(6): 329–334

  • Enzymatic preparation of silybin phase II metabolites: sulfation using aryl sulfotransferase from rat liver

    K. Purchartová, L. Engels, P. Marhol, M. Šulc, M. Kuzmam, K. Slámová, L. Elling, V. Křen

    Appl Microbiol Biotechnol, 2013, 97:10391–10398

  • Chemoenzymatic synthesis of a-L-rhamnosides using recombinant a-L-rhamnosidase from Aspergillus terreus

    Karel De Winter, Daniela Šimčíková, Bram Schalck, Lenka Weignerová, Helena Pelantova, Wim Soetaert, Tom Desmet, Vladimír Křen

    Bioresource Technology, 2013, 147, 640–644

  • Crystallization and preliminary X-ray crystallographic analysis of recombinant b-mannosidase from Aspergillus niger

    Gabriel Demo, Barbora Fliedrova, Lenka Weignerova and Michaela Wimmerova

    Acta Cryst., 2013, F69, 288–291

  • Heterologous expression, purifi cation and characterization of arylacetonitrilases from Nectria haematococca and Arthroderma benhamiae

    A. B. Veselá, A. Petříčková, P. Weyrauch, L. Martínková

    Biocatalysis and Biotransformation, 2013, 31(1): 49–56

  • LC–MS metabolic study on quercetin and taxifolin galloyl esters usinghuman hepatocytes as toxicity and biotransformation in vitro cellmodel

    Jan Vacek, Barbora Papouskova, Jiri Vrba, Martina Zatloukalova, Vladimir Kren, Jitka Ulrichová

    Journal of Pharmaceutical and Biomedical Analysis, 2013, 86, 135– 142

  • Preparative Purification and Isolation of Pyranoanthocyanins from Red Wine and Evaluation of Their Antioxidant Activity

    Petr Marhol, Petr Bednar, Eva Tomankova, Barbora Papouskova, Jan Stavek, Pavel Hıc, Petr Bartak, Vladimır Kren, Josef Balık

    Chromatographia, 2013, 76:1107–1115

  • β-N-Acetylhexosaminidases: group specific inhibitors

    K. Slámová, V. Křen

    chapter in , 2013, 39, 102-119

  • Antioxidant, metal-binding and DNA-damaging properties of flavonolignans: A joint experimental and computational highlight based on 7-O-galloylsilybin

    Jan Vacek, Martina Zatloukalová, Thomas Desmier, Veronika Nezhodová, Jan Hrbac, Martin Kubala Vladimír Kren, Jitka Ulrichová, Patrick Trouillas

    Chemico-Biological Interactions, 2013, 205, 173–180

  • Oxidative Addition of Diphenyldichalcogenides PhEEPh (E = S, Se, Te) to Low-Valent CN- and NCN-Chelated Organoantimony and Organobismuth Compounds

    Petr Šimon, Roman Jambor, AlešRůžička, and Libor Dostál

    Organometallics, 2013, 32, 239−248

  • Anti-Cancer Efficacy of Silybin Derivatives – A Structure-Activity Relationship

    Chapla Agarwal, Ritambhara Wadhwa, Gagan Deep, David Biedermann, Radek Gažák, Vladimír Křen, Rajesh Agarwal

    PLoS ONE, 2013, 8(3): e60074

  • Study of addition of difluorocarbene on double bond of triterpenes

    D. Biedermann, M. Urban, M. Budesinsky, M. Kvasnica, J. Sarek

    Journal of Fluorine Chemistry, 2013, 148, 30–35

  • Ionic liquids as cosolvents for glycosylation by sucrose phosphorylase: balancing acceptor solubility and enzyme stability

    Karel De Winter, Kristien Verlinden, Vladimír Křen, Lenka Weignerová, Wim Soetaert and Tom Desmet

    Green Chem., 2013, 15, 1949

  • A Comparative Study of Nitrilases Identified by Genome Mining

    Ondřej Kaplan, Alicja B. Veselá, Alena Petříčková, Fabrizia Pasquarelli, Martina Pičmanová, Anna Rinágelová, Tek Chand Bhalla, Miroslav Pátek, Ludmila Martínková

    Molecular Biotechnology, 2013, 54, 3, 996-1003

  • Enzymatic glycosylation of multivalent scaffolds

    Pavla Bojarová, Ruben R. Rosencrantz, Lothar Elling and Vladimír Křen

    Chem. Soc. Rev., 2013, 42, 4774

  • Corrigendum to “Enzymatic synthesis of dimeric glycomimetic ligands of NK cell activation receptors” [Carbohydr. Res. 346 (2011) 1599–1609]

    Anna Drozdová, Pavla Bojarová, Karel Křenek, Lenka Weignerová, Birgit Henßen, Lothar Elling, Helle Christensen, Henrik H. Jensen, Helena Pelantová, Marek Kuzma, Karel Bezouška, Monika Krupová, David Adámek, Kristýna Slámová, Vladimír Křen

    Carbohydrate Research, 2013, 373, 108

  • Bacterial communities in tetrachloroethene-polluted groundwaters: A case study

    Michael Kotik, Anna Davidová, Jana Voříšková, Petr Baldrian

    Science of the Total Environment, 2013, 454-455, 517–527

  • Directed evolution of metagenome-derived epoxide hydrolase for improved enantioselectivity and enantioconvergence

    Michael Kotik, Wei Zhao, Gilles Iacazio, Alain Archelas

    Journal of Molecular Catalysis B: Enzymatic, 2013, 91, 44–51

  • A Novel Semisynthetic Flavonoid 7‑O‑Galloyltaxifolin Upregulates Heme Oxygenase‑1 in RAW264.7 Cells via MAPK/Nrf2 Pathway

    Jiří Vrba, Radek Gažák, Marek Kuzma, Barbora Papoušková, Jan Vacek, Martin Weiszenstein, Vladimír Křen and Jitka Ulrichová

    J. Med. Chem., 2013, 56, 856−866

  • Biotransformation of benzonitrile herbicides via the nitrile hydratase–amidase pathway in rhodococci

    Alicja B. Veselá, Helena Pelantová, Miroslav Šulc, Martina Macková, Petra Lovecká, Markéta Thimová, Fabrizia Pasquarelli, Martina Pičmanová, Miroslav Pátek, Tek Chand Bhalla, Ludmila Martínková

    J. Ind. Microbiol. Biotechnol. , 2013, 39:1811–1819

  • Preparation of silybin and isosilybin sulfates by sulfotransferase from Desulfitobacterium hafniense

    Petr Marhol, Aloysius F. Hartog, Michael A. van der Horst, Ron Wever, Kateřina Purchartová, Kateřina Fuksová, Marek Kuzma, Josef Cvačka, Vladimír Křen

    Journal of Molecular Catalysis B: Enzymatic, 2013, 89, 24–27

  • Enzymatic synthesis of new C-6-acylated derivatives of NAG-thiazoline and evaluation of their inhibitor activities towards fungal

    Jana Krejzová, Petr Šimon, Eva Vavříková, Kristýna Slámová, Helena Pelantová, Sergio Riva, Vojtěch Spiwok, Vladimír Křen

    Journal of Molecular Catalysis B: Enzymatic, 2013, 87, 128– 134

  • Base-catalyzed oxidation of silybin and isosilybin into 2,3-dehydro derivatives

    Radek Gažák, Patrick Trouillas, David Biedermann, Kateřina Fuksová, Petr Marhol, Marek Kuzma, Vladimír Křen

    Tetrahedron Letters, 2013, 54, 315–317

  • Carbohydrate synthesis and biosynthesis technologies for cracking of the glycan code: Recent advances

    Hynek Mrázek, Lenka Weignerová, Pavla Bojarová, Petr Novák, Ondřej Vaněk, Karel Bezouška

    Biotechnology Advances, 2013, 31, 17–37

  • Preparative method for isosilybin isolation based on enzymatic kinetic resolution of silymarin mixture

    Radek Gažák, Kateřina Fuksová, Petr Marhol, Marek Kuzma, Rajesh Agarwal, Vladimír Křen

    Process Biochemistry, 2013, 48, 184–189