Laboratory of Biotransformation

Congratulations!

prestigious award “Lifetime Achievement”

Prof. Ing. Vladimír Křen, DrSc.

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Laboratory of Biotransformation is a part of the Institute of Microbiology of the Czech Academy of Sciences.

Research in the Laboratory of biotransformation integrates chemistry and biology to create frontier areas of molecular biocatalysis, rich in new ideas and results. Novel methodologies, search for new enzymes and new enzymatic reactions, advanced engineered biocatalysts, modern methods of structural analysis and separation procedures generate a number of new compounds that are eventually tested for various biological activities. Extensive collaborations – intramural, national and international – broaden the portfolio of methods and improve the visibility of our research. The Laboratory consists of three informal taskforce subgroups coordinated by senior researchers, i.e. “White team” (Glycobiology – Bojarová), “Blue team“ (Nitrile biotransformations – Martínková), and “Yellow team“ (Flavonoids and metabolomics – Valentová). An integrating point of the whole group is biocatalysis. More information…

 


News from lab

Bioorganic Chemistry, 140, 106819: 1-14 (2023)

IF 5,1 Highly functionalized diaminocyclopentanes: A new route to potent and selective inhibitors of human O-GlcNAcase Patrick Weber, Zuzana Mészáros,...
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Biotechnology Advances, 68, 108217, 1-20 (2023)

IF 16,00 Rutinosidase and other diglycosidases: Rising stars in biotechnology Vladimír Křen, Pavla Bojarová  Abstract Diglycosidases are a special class...
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Molecules, 28, 10, 4039: 1-15 (2023)

IF 4,6 Oligosaccharide Ligands of Galectin-4 and Its Subunits: Multivalency Scores Highly Kristýna Slámová, Jakub Červený, Zuzana Mészáros, Tereza Friede,...
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Bioorganic Chemistry, 131, 106279: 1-12 (2023)

IF 5,1 Advanced high-affinity glycoconjugate ligands of galectins Michaela Hovorková, Jakub Červený, Ladislav Bumba, Helena Pelantová, Josef Cvačka, Vladimír Křen,...
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INT J MOL SCI, 24, 9, 8030: 1-3 (2023)

IF 5,6 Editorial Biotransformation of Natural Products and Phytochemicals: Metabolites, Their Preparation and Properties  Kateřina Valentová  Abstract The term “biotransformation”...
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4th FBHC Prague 2023

  After the great success of the previous editions of the International Conference on Food Bioactives & Health and especially...
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„Lifetime Achievement“ Award

  10th International Congress on Biocatalysis (biocat), Hamburg, 28.8.-1.9.2022   At the International Congress on Biocatalysis, outstanding individuals are given...
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