Laboratory of Biotransformation

Congratulations!

prestigious award “Lifetime Achievement”

Prof. Ing. Vladimír Křen, DrSc.

more information…

 

Laboratory of Biotransformation is a part of the Institute of Microbiology of the Czech Academy of Sciences.

Research in the Laboratory of biotransformation integrates chemistry and biology to create frontier areas of molecular biocatalysis, rich in new ideas and results. Novel methodologies, search for new enzymes and new enzymatic reactions, advanced engineered biocatalysts, modern methods of structural analysis and separation procedures generate a number of new compounds that are eventually tested for various biological activities. Extensive collaborations – intramural, national and international – broaden the portfolio of methods and improve the visibility of our research. The Laboratory consists of three informal taskforce subgroups coordinated by senior researchers, i.e. “White team” (Glycobiology – Bojarová), “Blue team“ (Nitrile biotransformations – Martínková), and “Yellow team“ (Flavonoids and metabolomics – Valentová). An integrating point of the whole group is biocatalysis. More information…

 


News from lab

Catalysts, 13, 3, 500:1-19 (2023)

IF 4,501 Recent Progress in the Production of Cyanide-Converting Nitrilases—Comparison with Nitrile-Hydrolyzing Enzymes Ludmila Martínková, Natalia Kulik, Anastasia Sedova, Barbora...
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Molecules, 28, 4, 1728:1-14 (2023)

IF 4,927 Hesperidin, Hesperetin, Rutinose, and Rhamnose Act as Skin Anti-Aging Agents Renáta Novotná, Denisa Škařupová, Jiří Hanyk, Jitka Ulrichová,...
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Org Biomol Chem 21, 6, 1294-1302 (2023)

IF 3,890 Glycocalix[4]arenes and their affinity to a library of galectins: the linker matters Dorota Konvalinková, František Dolníček, Michaela Hovorková,...
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Adv Synth Catal 365, 1, 37-42 (2023)

IF 5,981 Organic Acid to Nitrile: A Chemoenzymatic Three-Step Route Winkler Margit, Horvat Melissa, Schiefer Astrid, Weilch Victoria, Rudroff Florian,...
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CRIT REV ENV SCI TEC, 53, 3, 416-434 (2023)

IF 11,750 Recent trends in the treatment of cyanide-containing effluents: Comparison of different approaches Ludmila Martínková, Pavla Bojarová, Anastasia Sedova,...
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Journal of Functional Foods, 100, 105391, 1-16 (2023)

IF 5,223 Metabolic profiling of silymarin constituents in urine and feces of healthy volunteers: A 90-day study Kateřina Lněničková, Jiří...
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4th FBHC Prague 2023

  After the great success of the previous editions of the International Conference on Food Bioactives & Health and especially...
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„Lifetime Achievement“ Award

  10th International Congress on Biocatalysis (biocat), Hamburg, 28.8.-1.9.2022   At the International Congress on Biocatalysis, outstanding individuals are given...
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