2014 Publications (24) : biotrans

Intramolecular Azide to Alkene Cycloadditions for the Construction of Pyrrolobenzodiazepines and Azetidino-Benzodiazepines

Karl Hemming, Christopher S. Chambers, Faisal Jamshaid, Paul A. O’Gorman

Molecules, 2014, 19, 10, 16737-16756
Protein engineering study of β-mannosidase to set up a potential chemically efficient biocatalyst

Gabriel Demo, Veronika Horská, Barbora Fliedrová, Jakub Štěpán, Jaroslav Koča, Lenka Weignerová, Vladimír Křen, Michaela Wimmerová

Glycobiology, 2014, 24, 12, 1301-1311
Inhibition of microbial b-N-acetylhexosaminidases by 4-deoxy- and galacto-analogues of NAG-thiazoline

Jana Krejzová, Ľubica Kalachová, Petr Šimon, Helena Pelantová, Kristýna Slámová, Vladimír Křen

Bioorganic & Medicinal Chemistry Letters, 2014, 24, 22, 5321-5323
Preparatory separation of the silymarin flavonolignans by Sephadex LH-20 gel

Karel Křenek, Petr Marhol, Žaneta Peikerová, Vladimír Křen, David Biedermann

Food Research International, 2014, 65, Part A, 115-120
The influence of vitamin-rich diet on the extent of lipoperoxidation in brain of mice during an acute post-insulin hypoglycaemia

Jitka Patočková, Jiří Slíva, Petr Marhol, Jiřina Crkovská, Stanislav Štípek

European Journal of Pharmacology, 2014, 740, 641-644
Enzymatic oxidative dimerization of silymarin flavonolignans

Paolo Gavezzotti, Eva Vavříková, Kateřina Valentová, Giovanni Fronza, Tukayi Kudanga, Marek Kuzma, Sergio Riva, David Biedermann, Vladimír Křen

Journal of Molecular Catalysis B: Enzymatic, 2014, 109, 24-30
Biphasic Catalysis with Disaccharide Phosphorylases: Chemoenzymatic Synthesis of α‑D‑Glucosides Using Sucrose Phosphorylase

Karel De Winter, Tom Desmet, Tim Devlamynck, Lisa Van Renterghem, Tom Verhaeghe, Helena Pelantová, Vladimír Křen, Wim Soetaert

Organic Process Research & Development, 2014, 18, 6, 781-787
Nitrile Converting Enzymes Involved in Natural and Synthetic Cascade Reactions

Ludmila Martínková, Andreas Stolz, Fred van Rantwijk, Nicola D’Antona, Dean Brady, Linda G. Otten

Cascade Biocatalysis, 2014, 249 – 270
Key-Study on the Kinetic Aspects of the In Situ NHase/AMase Cascade System of M.imperiale Resting Cells for Nitrile Bioconversion

Laura Cantarella, Fabrizia Pasquarelli, Agata Spera, Ludmila Martínková, Maria Cantarella

Cascade Biocatalysis, 2014, 283-295
Mining Genomes for Nitrilases

Ludmila Martínková

Cascade Biocatalysis, 2014, 271-281
Chemistry of silybin

David Biedermann, Eva Vavříková, L. Cvak, Vladimír Křen

Natural Product Reports, 2014, 31, 9, 1138-1157
Access to bifunctionalized biomolecular platforms using oxime ligation

Karel Křenek, Radek Gažák, Gour Chand Daskhan, Julian Garcia, Michele Fiore, Pascal Dumy, Miroslav Šulc, Vladimír Křen, Olivier Renaudet

Carbohydrate Research, 2014, 393, 9-14
Expression control of nitrile hydratase and amidase genes in Rhodococcus erythropolis and substrate specificities of the enzymes

Lenka Rucká, Olga Volkova, Adam Pavlík, Ondřej Kaplan, Martin Kracík, Jan Nešvera, Ludmila Martínková, Miroslav Pátek

Antonie van Leeuwenhoek, 2014, 105, 6, 1179-1190
cis–trans Isomerization of silybins A and B

Michaela Novotná, Radek Gažák, David Biedermann, Florent Di Meo, Petr Marhol, Marek Kuzma, Lucie Bednárová, Kateřina Fuksová, Patrick Trouillas, Vladimír Křen

Beilstein Journal of Organic Chemistry, 2014, 10, 1047-1063
Isoquercitrin: Pharmacology, toxicology, and metabolism

Kateřina Valentová, Jiří Vrba, Martina Bancířová, Jitka Ulrichová, Vladimír Křen

Food and Chemical Toxicology, 2014, 68, 267-282
Rapid enzymatic hydrolysis of masked deoxynivalenol and zearalenone prior to liquid chromatography mass spectrometry or immunoassay analysis

Nielen M.W.F., Weijers C.A.G.M., Peters J., Weignerová L., Zuilhof H., Franssen M.C.R.

World Mycotoxin Journal, 2014, 7, 2, 107-113
Chemo-Enzymatic Synthesis of Silybin and 2,3-Dehydrosilybin Dimers

Eva Vavříková, Jan Vacek, Kateřina Valentová, Petr Marhol, Jitka Ulrichová, Marek Kuzma, Vladimír Křen

Molecules, 2014, 19, 4, 4115-4134
Preparation of silybin phase II metabolites: Streptomyces catalyzed glucuronidation

Cedric Charrier, Robert Azerad, Petr Marhol, Kateřina Purchartová, Marek Kuzma, Vladimír Křen

Journal of Molecular Catalysis B: Enzymatic, 2014, 102, 167-173
Cyanide hydratase from Aspergillus niger K10: Overproduction in Escherichia coli, purification, characterization and use in continuous cyanide degradation

Anna Rinágelová, Ondřej Kaplan, Alicja B. Veselá, Martin Chmátal, Alena Křenková, Ondřej Plíhal, Fabrizia Pasquarelli, Maria Cantarella, Ludmila Martínková

Process Biochemistry, 2014, 49, 3, 445-450
Inhibition of GlcNAc-Processing Glycosidases by C-6-Azido-NAG-Thiazoline and Its Derivatives

Jana Krejzová, Petr Šimon, Ľubica Kalachová, Natallia Kulik, Pavla Bojarová, Petr Marhol, Helena Pelantová, Josef Cvačka, Rüdiger Ettrich, Kristýna Slámová, Vladimír Křen

Molecules, 2014, 19, 3, 3471-3488
Bioavailability of silymarin flavonolignans: drug formulations and biotransformation

Eleni Theodosiou, Kateřina Purchartová, Haralambos Stamatis, Fragiskos Kolisis, Vladimír Křen

Phytochem Rev, 2014, 13, 1, 1-18
Chemo-enzymatic synthesis of LacdiNAc dimers of varying length asnovel galectin ligands

A. Šimonová, C. E. Kupper, S. Böcker, A. Müller, K. Hofbauerová, H. Pelantová, L. Elling, V. Křen, P. Bojarová

Journal of Molecular Catalysis B: Enzymatic, 2014, 101, 47– 55
Expression, characterization and homology modeling of a novel eukaryotic GH84 b-N-acetylglucosaminidase from Penicillium chrysogenum

K. Slámová, N. Kulik, M. Fiala , J. Krejzová-Hofmeisterová, R. Ettrich, V. Křen

Protein Expression and Puriﬁcation, 2014, 95, 204–210
Re-Evaluation of Binding Properties of Recombinant Lymphocyte Receptors NKR-P1A and CD69 to Chemically Synthesized Glycans and Peptides

D. Rozbeský, J. Krejzová, K. Křenek, J. Prchal, R. Hrabal, M. Kožíšek, L. Weignerová, M. Fiore, P. Dumy, O. Renaudet and V. Křen

Int. J. Mol. Sci., 2014, 15, 1271-1283

2014 Publications (24)

Intramolecular Azide to Alkene Cycloadditions for the Construction of Pyrrolobenzodiazepines and Azetidino-Benzodiazepines

Protein engineering study of β-mannosidase to set up a potential chemically efficient biocatalyst

Inhibition of microbial b-N-acetylhexosaminidases by 4-deoxy- and galacto-analogues of NAG-thiazoline

Preparatory separation of the silymarin flavonolignans by Sephadex LH-20 gel

The influence of vitamin-rich diet on the extent of lipoperoxidation in brain of mice during an acute post-insulin hypoglycaemia

Enzymatic oxidative dimerization of silymarin flavonolignans

Biphasic Catalysis with Disaccharide Phosphorylases: Chemoenzymatic Synthesis of α‑D‑Glucosides Using Sucrose Phosphorylase

Nitrile Converting Enzymes Involved in Natural and Synthetic Cascade Reactions

Key-Study on the Kinetic Aspects of the In Situ NHase/AMase Cascade System of M.imperiale Resting Cells for Nitrile Bioconversion

Mining Genomes for Nitrilases

Chemistry of silybin

Access to bifunctionalized biomolecular platforms using oxime ligation

Expression control of nitrile hydratase and amidase genes in Rhodococcus erythropolis and substrate specificities of the enzymes

cis–trans Isomerization of silybins A and B

Isoquercitrin: Pharmacology, toxicology, and metabolism

Rapid enzymatic hydrolysis of masked deoxynivalenol and zearalenone prior to liquid chromatography mass spectrometry or immunoassay analysis

Chemo-Enzymatic Synthesis of Silybin and 2,3-Dehydrosilybin Dimers

Preparation of silybin phase II metabolites: Streptomyces catalyzed glucuronidation

Cyanide hydratase from Aspergillus niger K10: Overproduction in Escherichia coli, purification, characterization and use in continuous cyanide degradation

Inhibition of GlcNAc-Processing Glycosidases by C-6-Azido-NAG-Thiazoline and Its Derivatives

Bioavailability of silymarin flavonolignans: drug formulations and biotransformation

Chemo-enzymatic synthesis of LacdiNAc dimers of varying length asnovel galectin ligands

Expression, characterization and homology modeling of a novel eukaryotic GH84 b-N-acetylglucosaminidase from Penicillium chrysogenum

Re-Evaluation of Binding Properties of Recombinant Lymphocyte Receptors NKR-P1A and CD69 to Chemically Synthesized Glycans and Peptides

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