2016 Publications (28)

  • Enhanced Mitogenic Activity of Recombinant Human Vascular Endothelial Growth Factor VEGF121 Expressed in E. coli Origami B (DE3) with Molecular Chaperones

    Ondřej Kaplan, Jana Zárubová, Barbora Mikulová, Elena Filová, Jiřina Bártová, Lucie Bačáková, Eduard Brynda

    PLOS ONE, 2016, 11, 10, e0163697, 1-22

  • Silychristin: Skeletal Alterations and Biological Activities

    David Biedermann, Martin Buchta, Veronika Holečková, David Sedlák, Kateřina Valentová, Josef Cvačka, Lucie Bednárová, Alena Křenková, Marek Kuzma, Ctibor Škuta, Žaneta Peikerová, Petr Bartůněk, Vladimír Křen

    Journal of Natural Products, 2016, 79, 12, 3086-3092

  • Laccase-catalyzed dimerization of glycosylated lignols

    Ivan Bassanini, Paolo Gavezzotti, Daniela Monti, Jana Krejzová, Vladimír Křen, Sergio Riva

    Journal of Molecular Catalysis B: Enzymatic, 2016, 134, part B, 295-301

  • Flavonolignan Conjugates as DNA-binding Ligands and Topoisomerase I Inhibitors: Electrochemical and Electrophoretic Approaches

    Martina Zatloukalová, Eva Vavříková, Ana Dora Rodrigues Pontinha, Jan Coufal, Vladimír Křen, Miroslav Fojta, Jitka Ulrichová, Ana Maria Oliveira-Brett, Jan Vacek

    Electroanalysis, 2016, 28, 11, 2866-2874

  • Semisynthetic flavonoid 7-O-galloylquercetin activates Nrf2 and induces Nrf2-dependent gene expression in RAW264.7 and Hepa1c1c7 cells

    Lenka Roubalová, David Biedermann, Barbora Papoušková, Jan Vacek, Marek Kuzma, Vladimír Křen, Jitka Ulrichová, Albena T. Dinkova-Kostova, Jiří Vrba

    Chemico-Biological Interactions, 2016, 260, 58-66

  • Sugared biomaterial binding lectins: achievements and perspectives

    Pavla Bojarová, Vladimír Křen

    Biomaterials Science, 2016, 4, 8, 1142-1160

  • Epoxide Hydrolases and Its Application in Organic Synthesis

    Alain Archelas, Gilles Iacazio, Michael Kotík

    Green Biocatalysis, 2016, 179 – 230

  • Protective effect of isoquercitrin against acute dextran sulfate sodium-induced rat colitis depends on the severity of tissue damage

    Norbert Cibiček, Lenka Roubalová, Jiří Vrba, Martina Zatloukalová, Jiří Ehrmann, Jana Zapletalová, Rostislav Večeřa, Vladimír Křen, Jitka Ulrichová

    Pharmacological Reports, 2016, 68, 6, 1197-1204

  • In vitro study of 2,3-dehydrosilybin and its galloyl esters as potential inhibitors of angiogenesis

    V. Pivodová, S. Zahler, D. Karas, K. Valentová, J. Ulrichová

    Pharmazie, 2016, 71, 478-483

  • Nitrile-Converting Enzymes and Its Synthetic Applications

    Ludmila Martínková

    Green Biocatalysis, 2016, 331-350

  • Tunable optical properties of silymarin flavonolignans

    Michal Biler, Patrick Trouillas, David Biedermann, Vladimír Křen, Martin Kubala

    Journal of Photochemistry and Photobiology A: Chemistry, 2016, 328, 154-162

  • The integration of cyanide hydratase and tyrosinase catalysts enables effective degradation of cyanide and phenol in coking wastewaters

    Ludmila Martínková, Martin Chmátal

    Water Research, 2016, 102, 90-95

  • Isoquercitrin Esters with Mono- or Dicarboxylic Acids: Enzymatic Preparation and Properties

    Eva Vavříková, Fanny Langschwager, Ľubica Ježová-Kalachová, Alena Křenková, Barbora Mikulová, Marek Kuzma, Vladimír Křen, Kateřina Valentová

    International Journal of Molecular Sciences, 2016, 17, 6, 899, 1-12

  • Oxidation of the Flavonolignan Silybin. In situ EPR Evidence of the Spin-Trapped Silybin Radical

    Romana Sokolová, Ján Tarábek, Barbora Papoušková, Jana Kocábová, Jan Fiedler, Jan Vacek, Petr Marhol, Eva Vavříková, Vladimír Křen

    Electrochimica Acta, 2016, 205, 118-123

  • Recombinant Tyrosinase from Polyporus arcularius: Overproduction in Escherichia coli, Characterization, and Use in a Study of Aurones as Tyrosinase Effectors

    Eva Marková, Michael Kotik, Alena Křenková, Petr Man, Romain Haudecoeur, Ahcène Boumendjel, Renaud Hardré, Yasmina Mekmouche, Elise Courvoisier-Dezord, Marius Réglier, Ludmila Martínková

    Journal of Agricultural and Food Chemistry, 2016, 64, 14, 2925-2931

  • Effects of 2,3-Dehydrosilybin and Its Galloyl Ester and Methyl Ether Derivatives on Human Umbilical Vein Endothelial Cells

    Daniel Karas, Radek Gažák, Kateřina Valentová, Christopher S. Chambers, Veronika Pivodová, David Biedermann, Alena Křenková, Ivana Oborná, Marek Kuzma, Josef Cvačka, Jitka Ulrichová, Vladimír Křen

    Journal of Natural Products, 2016, 79, 4, 812-820

  • Unconventional application of the Mitsunobu reaction: Selective flavonolignan dehydration yielding hydnocarpins

    Guozheng Huang, Simon Schramm, Jörg Heilmann, David Biedermann, Vladimír Křen, Michael Decker

    Beilstein Journal of Organic Chemistry, 2016, 12, 662-669

  • Flavonolignans As a Novel Class of Sodium Pump Inhibitors

    Martin Kubala, Petra Čechová, Jaroslava Geletičová, Michal Biler, Tereza Štenclová, Patrick Trouillas, David Biedermann

    Frontiers in Physiology, 2016, 7, 115

  • Expression of human beta-N-acetylhexosaminidase B in yeast eases the search for selective inhibitors

    Jana Krejzová, Natallia Kulik, Kristýna Slámová, Vladimír Křen

    Enzyme and Microbial Technology, 2016, 89, 1-6

  • Bacteria as source of diglycosidase activity: Actinoplanes missouriensis produces 6-O-α-L-rhamnosyl-β-D-glucosidase active on flavonoids

    Bárbara D. Neher, Laura S. Mazzaferro, Michael Kotik, Jorge Oyhenart, Petr Halada, Vladimír Křen, Javier D. Breccia

    Applied Microbiology and Biotechnology , 2016, 100, 7, 3061-3070

  • (Anti)mutagenic and immunomodulatory properties of quercetin glycosides

    Kateřina Valentová, Petr Šíma, Zuzana Rybková, Jiří Křížan, Kateřina Malachová, Vladimír Křen

    Journal of the Science of Food and Agriculture, 2016, 96, 5, 1492-1499

  • Towards Keratan Sulfate – Chemoenzymatic Cascade Synthesis of Sulfated N-Acetyllactosamine (LacNAc) Glycan Oligomers

    Bastian Lange, Anna Šimonov‚á, Thomas Fischoder, Helena Pelantová, Vladim†ír Křen, Lothar Elling

    Advanced Synthesis and Catalysis, 2016, 358, 4, 584-596

  • Bringing nitrilase sequences from databases to life: the search for novel substrate specificities with a focus on dinitriles

    Alicja B. Veselá, Lenka Rucká, Ondřej Kaplan, Helena Pelantová, Jan Nešvera, Miroslav Pátek, Ludmila Martínková

    Applied Microbiology and Biotechnology, 2016, 100, 5, 2193-2202

  • Biodegradation of phenolic compounds by Basidiomycota and its phenol oxidases: A review

    Ludmila Martínková, Michael Kotik, Eva Marková, Ladislav Homolka

    Chemosphere, 2016, 149, 373-382

  • Phototoxic potential of silymarin and its bioactive components

    Alena Rajnochová Svobodová, Bohumil Zálešák, David Biedermann, Jitka Ulrichová, Jitka Vostálová

    Journal of Photochemistry & Photobiology, B: Biology, 2016, 156, 61-68

  • Epoxide hydrolase-catalyzed enantioselective conversion of trans-stilbene oxide: Insights into the reaction mechanism from steady-state and pre-steady-state enzyme kinetics

    Alain Archelas, Wei Zhao, Bruno Faure, Gilles Iacazio, Michael Kotik

    Archives of Biochemistry and Biophysics, 2016, 591, 66-75

  • Flavonolignan 2,3-dehydroderivatives: Preparation, antiradical and cytoprotective activity

    Michaela Pyszková, Michal Biler, David Biedermann, Kateřina Valentová, Marek Kuzma, Jiří Vrba, Jitka Ulrichová, Romana Sokolová, Miloš Mojović, Ana Popović-Bijelić, Martin Kubala, Patrick Trouillas, Vladimír Křen, Jan Vacek

    Free Radical Biology and Medicine, 2016, 90, 114-125

  • Silibinin and Its 2,3-Dehydro-Derivative Inhibit Basal Cell Carcinoma Growth via Suppression of Mitogenic Signaling and Transcription Factors Activation

    Cynthia Tilley, Gagan Deep, Chapla Agarwal, Michael F. Wempe, David Biedermann, Kateřina Valentová, Vladimír Křen, Rajesh Agarwal

    Molecular Carcinogenesis, 2016, 55, 1, 3-14