2019 Publications (31)

  • Acceptor Specificity of beta-N-Acetylhexosaminidase from Talaromyces flavus: A Rational Explanation

    Cecilia Garcia-Oliva, Pilar Hoyos, Lucie Petrásková, Natalia Kulik, Helena Pelantová, Alfredo H. Cabanillas, Ángel Rumbero, Vladimír Křen, María J. Hernáiz, Pavla Bojarová

    International Journal of Molecular Sciences, 2019, 20, 24, 6181: 1-17

  • Genetic and Functional Diversity of Nitrilases in Agaricomycotina

    Lenka Rucká, Martin Chmátal, Natalia Kulik, Lucie Petrásková, Helena Pelantová, Petr Novotný, Romana Příhodová, Miroslav Pátek, Ludmila Martínková

    International Journal of Molecular Sciences, 2019, 20, 23, 5990: 1-19

  • The flavonoid degrading fungus Acremonium sp. DSM 24697 produces two diglycosidases with different specificities

    Gisela Weiz, Laura S. Mazzaferro, Michael Kotik, Bárbara D. Neher, Petr Halada, Vladimír Křen, Javier D. Breccia

    Applied Microbiology and Biotechnology, 2019, 103, 23-24, 9493-9504

  • In vitro response of human ovarian cancer cells to dietary bioflavonoid isoquercitrin

    Katarina Michalcová, Shubhadeep Roychoudhury, Marek Halenar, Eva Tvrdá, Eva Kovaciková, Jaromír Vasicek, Peter Chrenek, Simona Baldovská, Luboslav Sanislo, Vladimír Křen, Adriana Kolesarová

    Journal of Environmental Science and Health, Part B, 2019, 54, 9, 752-757

  • Identifying Efficient Clostridium difficile Toxin A Binders with a Multivalent Neo-Glycoprotein Glycan Library

    Viktoria Heine, Sarah Boesveld, Helena Pelantová, Vladimír Křen, Christian Trautwein, Pavel Strnad, Lothar Elling

    Bioconjugate Chemistry, 2019, 30, 9, 2373-2383

  • The Effect of Silymarin Flavonolignans and Their Sulfated Conjugates on Platelet Aggregation and Blood Vessels Ex Vivo

    Jana Pourová, Lenka Applová, Kateřina Macáková, Marie Vopršalová, Thomas Migkos, Roger Bentanachs, David Biedermann, Lucie Petrásková, Václav Tvrdý, Marcel Hrubša, Jana Karlíčková, Vladimír Křen, Kateřina Valentová, Přemysl Mladěnka

    Nutrients, 2019, 11, 10, 2286, 1-16

  • β-N-Acetylhexosaminidases—the wizards of glycosylation

    Pavla Bojarová, Jan Bruthans, Vladimír Křen

    Applied Microbiology and Biotechnology, 2019, 103, 19, 7869-7881

  • A pilot study of the UVA‑photoprotective potential of dehydrosilybin, isosilybin, silychristin, and silydianin on human dermal fibroblasts

    Alena Rajnochová Svobodová, Eva Gabrielová, Jitka Ulrichová, Bohumil Zálešák, David Biedermann, Jitka Vostálová

    Archives of Dermatological Research, 2019, 311, 6, 477-490

  • Redox properties of individual quercetin moieties

    Eva Heřmánková, Martina Zatloukalová, Michal Biler, Romana Sokolová, Martina Bancířová, Andreas G. Tzakos, Vladimír Křen, Marek Kuzma, Patrick Trouillas, Jan Vacek

    Free Radical Biology and Medicine, 2019, 143, 240-251

  • Complex Evaluation of Antioxidant Capacity of Milk Thistle Dietary Supplements

    Jitka Viktorová, Milena Stránská-Zachariášová, Marie Fenclová, Libor Vítek, Jana Hajšlová, Vladimír Křen, Tomáš Ruml

    Antioxidants, 2019, 8, 8, 317, 1-18

  • Antioxidant, Anti-Inflammatory, and Multidrug Resistance Modulation Activity of Silychristin Derivatives

    Jitka Viktorová, Simona Dobiasová, Kateřina Řehořová, David Biedermann, Kristýna Káňová, Karolína Šeborová, Radka Václavíková, Kateřina Valentová, Tomáš Ruml, Vladimír Křen, Tomáš Macek

    Antioxidants, 2019, 8, 8, 303, 1-19

  • Poor chemical and microbiological quality of the commercial milk thistle-based dietary supplements may account for their reported unsatisfactory and nonreproducible clinical outcomes

    Marie Fenclová, Alena Nováková, Jitka Viktorová, Petra Jonatová, Zbyněk Dzuman, Tomáš Ruml, Vladimír Křen, Jana Hajšlová, Libor Vítek, Milena Stránská-Zachariášová

    Scientific Reports, 2019, 9,11118:1-12

  • Preparation of Retinoyl-Flavonolignan Hybrids and Their Antioxidant Properties

    Christopher S. Chambers, David Biedermann, Kateřina Valentová, Lucie Petrásková, Jitka Viktorová, Marek Kuzma, Vladimír Křen

    Antioxidants, 2019, 8, 7, 236: 1-12

  • Chemoenzymatic Synthesis and Radical Scavenging of Sulfated Hydroxytyrosol, Tyrosol, and Acetylated Derivatives

    Paloma Begines, David Biedermann, Kateřina Valentová, Lucie Petrásková, Helena Pelantová, Inés Maya, José G. Fernández-Bolaños, Vladimír Křen

    Journal of Agricultural and Food Chemistry, 2019, 67, 26, 7281-7288

  • Potential of Mitochondria-Targeted Antioxidants to Prevent Oxidative Stress in Pancreatic β-cells

    Lydie Plecitá-Hlavatá, Hana Engstová, Jan Ježek, Blanka Holendová, Jan Tauber, Lucie Petrásková, Vladimír Křen, Petr Ježek

    Oxidative Medicine and Cellular Longevity, 2019, 2019, ID1826303, 1-16

  • Glycosidase-Catalyzed Synthesis of Glycosyl Esters and Phenolic Glycosides of Aromatic Acids

    I. Bassanini, J. Kapešová, L. Petrásková, H. Pelantová, K. Markošová, M. Rebroš, K. Valentová, M. Kotik, K. Káňová, P. Bojarová, J. Cvačka, L. Turková, E.E. Ferrandi, I. Bayout, S. Riva, V. Křen

    Advanced Synthesis and Catalysis, 2019, 361, 11, 2627-2637

  • 2,3-Dehydroderivatives of Silymarin Flavonolignans: Prospective Natural Compounds for the Prevention of Chronic Diseases

    Kateřina Valentová, David Biedermann, Vladimír Křen

    Proceedings, 2019, 11, 1, 21, 1-4

  • The mechanisms of pharmacokinetic food-drug interactions – A perspective from the UNGAP group

    M.Koziolek, S.Alcaro, P.Augustijns, A.W.Basit, M.Grimm, B.Hens, C.L.Hoad, P.Jedamzik, C.M.Madla, M.Maliepaard, L.Marciani, A.Maruca, N.Parrott, P.Pávek, C.Porter, C.Reppas, D.van Riet-Nales, J.Rubbens, M.Statelova, N.L.Trevaskis, K.Valentová, M.Vertzoni,

    European Journal of Pharmaceutical Sciences, 2019, 134, 31-59

  • Nitrile metabolism in fungi: A review of its key enzymes nitrilases with focus on their biotechnological impact

    Ludmila Martínková

    Fungal Biology Reviews, 2019, 33, 2, 149-157

  • Galectin–Carbohydrate Interactions in Biomedicine and Biotechnology

    Dominic Laaf, Pavla Bojarová, Lothar Elling, Vladimír Křen

    Trends in Biotechnology, 2019, 37, 4, 402-415

  • Skin Protective Activity of Silymarin and its Flavonolignans

    Jitka Vostálová, Eva Tinková, David Biedermann, Pavel Kosina, Jitka Ulrichová, Alena Rajnochová Svobodová

    Molecules, 2019, 24, 6, 1022, 1-12

  • Dietary Polyphenols Targeting Arterial Stiffness: Interplay of Contributing Mechanisms and Gut Microbiome-Related Metabolism

    Tess De Bruyne, Bieke Steenput, Lynn Roth, Guido R.Y. De Meyer, Claudia Nunes dos Santos, Kateřina Valentová, Maija Dambrova, Nina Hermans

    Nutrients, 2019, 11, 3, 578, 1-43

  • Bioproduction of Quercetin and Rutinose Catalyzed by Rutinosidase: Novel Concept of “Solid State Biocatalysis”

    Jana Kapešová, Lucie Petrásková, Kristína Markošová, Martin Rebroš, Michael Kotik, Pavla Bojarová, Vladimír Křen

    International Journal of Molecular Sciences, 2019, 20, 5, 1112, 1-15

  • Enzyme-mediated transglycosylation of rutinose (6-O-α-L-rhamnosyl-D-glucose) to phenolic compounds by a diglycosidase from Acremonium sp. DSM 24697

    Mazzaferro S. Laura, Weiz Gisela, Braun Lucas, Kotik Michael, Pelantová Helena, Křen Vladimír, Breccia D. Javier

    Biotechnology and Applied Biochemistry, 2019, 66, 1, 53-59

  • Selective β-N-acetylhexosaminidase from Aspergillus versicolor—a tool for producing bioactive carbohydrates

    Pavla Bojarová, Natallia Kulik, Kristýna Slámová, Martin Hubálek, Michael Kotik, Josef Cvačka, Helena Pelantová, Vladimír Křen

    Applied Microbiology and Biotechnology, 2019, 103, 4, 1737-1753

  • The beta-N-Acetylhexosaminidase in the Synthesis of Bioactive Glycans: Protein and Reaction Engineering

    Pavla Bojarová, Natalia Kulik, Michaela Hovorková, Kristýna Slámová, Helena Pelantová, Vladimír Křen

    Molecules, 2019, 24, 3, 599, 1-14

  • Isolated Silymarin Flavonoids Increase Systemic and Hepatic Bilirubin Concentrations and Lower Lipoperoxidation in Mice

    Jakub Šuk, Jana Jašprová, David Biedermann, Lucie Petrásková, Kateřina Valentová, Vladimír Křen, Lucie Muchová, Libor Vítek

    Oxidative Medicine and Cellular Longevity, 2019, 2019, ID6026902, 1-12

  • Oxidation of flavonolignan silydianin to unexpected lactone-acid derivative

    David Biedermann, Veronika Moravcová, Kateřina Valentová, Marek Kuzma, Lucie Petrásková, Ivana Císařová, Vladimír Křen

    Phytochemistry Letters, 2019, 30, 14-20

  • Dermal Delivery of Selected Polyphenols from Silybum marianum. Theoretical and Experimental Study

    Pavel Kosina, Markéta Paloncýová, Alena Rajnochová Svobodová, Bohumil Zálešák, David Biedermann, Jitka Ulrichová, Jitka Vostálová

    Molecules, 2019, 24, 1, 61, 1-20

  • Modulation of Skin Inflammatory Response by Active Components of Silymarin

    Jana Juráňová, Juliette Aury-Landas, Karim Boumediene, Catherine Baugé, David Biedermann, Jitka Ulrichová, Jana Franková

    Molecules, 2019, 24, 1, 123, 1-18

  • In vitro and in silico studies of the membrane permeability of natural flavonoids from Silybum marianum (L.) Gaertn. and their derivatives

    Antonia Diukendjieva, Petko Alov, Ivanka Tsakovska, Tania Pencheva, Andrea Richarz, Vladimír Křen, Mark T.D. Cronin, Ilza Pajeva

    Phytomedicine, 2019, 53, 79-85