Dr. sc. nat. Michael Kotík, PhD.

Senior Scientist
(+420) 296 442 569
Laboratory of Biotransformation
Institute of Microbiology of the Czech Academy of Sciences
Vídeňská 1083
Praha 4 – Krč
142 20
Czech Republic


  • Graduated in biotechnology, Department of Life Sciences, Swiss Federal Institute of Technology (ETH) in Zurich (1987)
  • PhD-work at the Institute of Molecular Biology and Biophysics at the Swiss Federal Institute of Technology (ETH) in Zurich (1992)

Research Orientation

  • Biocatalytic production of enantiomerically pure compounds and synthons
  • Molecular biology and enzyme characterisation techniques: cloning, overproduction and kinetics of biotechnologically relevant enzymes (epoxide hydrolases, haloalkane dehalogenases, glycosidases and tyrosinases)
  • Laboratory evolution of enzymes
  • Metagenomes and microbial communities

Projects and co-operations

  • Access to enantiopure epoxides and vicinal diols using epoxide hydrolases – co-operation with A. Archelas and G. Iacazio (Marseille, France)
  • Diglycosidases: microbial disaccharide-specific glycosidases – co-operation with J. Breccia (Santa Rosa, Argentina)
  • Novel haloalkane dehalogenases and microbial communities from polluted groundwaters – co-operation with P. Baldrian (Prague) and J. Damborský (Brno)
  • Tyrosinases as tools for wastewater treatment: see the web page of Dr. L. Martínková



Last update: March 27, 2023