Ing. Katerina Brodsky

Position:
Scientific Staff
Email:
katerina.brodsky@biomed.cas.cz
Phone:
(+420) 296 442 405
Address:
Laboratory of Biotransformation
Institute of Microbiology of the Czech Academy of Sciences
Vídeňská 1083
Praha 4 – Krč
142 00
Czech Republic

Education

  • PhD. student of Biochemistry and Bioorganic Chemistry
    Department of Biochemistry and Microbiology, UCT Prague, Czech Republic
    Thesis: Aryl-sulfotransferases and their application in sulfated metabolite preparation
  • Master’s degree (Ing.) in Microbiology – 2019
    Department of Biochemistry and Microbiology, UCT Prague, Czech Republic
  • Bachelor’s degree in Biochemistry and Biotechnology – 2016
    Department of Biochemistry and Microbiology, Faculty of Food and Biochemical Technology (FFBT), University of Chemistry and Technology (UCT Prague), Prague, Czech Republic

Research interest and skills

  • Recombinant enzymes and enzymatic syntheses (from gene to product)
  • Hydrolysis and transglycosylation capability of fungal glycosidases (Aspergillus)
  • Metabolism and biotransformation of polyphenols, sulfated metabolites
  • Enzymatic biotransformation of sugars and polyphenols

Languages

  • English – Fluent
  • Czech – Fluent
  • Hebrew (native)
  • Russian (native)

International Stays

2020 – Slovak University of Technology in Bratislava, Slovak Republic (3 weeks)
2023 – NOVA medical school, Lisbon, Portugal – Dr. Ana Sofia Falcão (4 weeks)

Publications

  • 9 publications
  • 50 citations

ORCID: 0000-0002-9071-7595

h-index: 5 (WOS, 03/2025)

  • Katerina Brodsky, Barbora Petránková, Lucie Petrásková, Helena Pelantová, Vladimír Křen, Kateřina Valentová, Pavla Bojarová: New Bacterial Aryl Sulfotransferases: Effective Tools for Sulfation of Polyphenols. Journal of Agricultural and Food Chemistry, 72 (40), 22208-22216 (2024).
  • Katerina Brodsky, Lucie Petrásková, Michal Kutý, Pavla Bojarová, Helena Pelantová, Vladimír Křen: Expanding Rutinosidase Versatility: Acylated Quercetin Glucopyranosides as Substrates. ChemCatChem, 16 (11), e202400028: 1-7 (2024).
  • Renáta Novotná, Denisa Škařupová, Jiří Hanyk, Jitka Ulrichová, Vladimír Křen, Pavla Bojarová, Katerina Brodsky, Jitka Vostálová, Jana Franková: Hesperidin, Hesperetin, Rutinose, and Rhamnose Act as Skin Anti-Aging Agents. Molecules, 28 (4), 1728:1-14 (2023).
  • Viola Kolaříková, Katerina Brodsky, Lucie Petrásková, Helena Pelantová, Josef Cvačka, Libor Havlíček, Vladimír Křen, Kateřina Valentová: Sulfation of Phenolic Acids: Chemoenzymatic vs. Chemical Synthesis. International Journal of Molecular Sciences, 23 (23), 15171: 1-16 (2022). 
  • Katerina Brodsky, Kristýna Káňová, Dorota Konvalinková, Kristýna Slámová, Helena Pelantová, Kateřina Valentová, Pavla Bojarová, Vladimír Křen, Lucie Petrásková: Bacterial Aryl Sulfotransferases in Selective and Sustainable Sulfation of Biologically Active Compounds using Novel Sulfate Donors. ChemSusChem, 15 (18), e202201253: 1-9 (2022). 
  • Lucie Petrásková, Kristýna Káňová, Katerina Brodsky, Anastasiia Hetman, Barbora Petránková, Helena Pelantová, Vladimír Křen, Kateřina Valentová: Sulfated Phenolic Substances: Preparation and Optimized HPLC Analysis. International Journal of Molecular Sciences, 23 (10), 5743:1-18 (2022). 
  • Kotík Michael, Brodsky Katerina, Halada Petr, Javůrková Hana, Pelantová Helena, Konvalinková Dorota, Bojarová Pavla, Křen Vladimír: Acces to both anomers of rutinosyl azide using wild-type rutinosidase and its catalytic nucleophile mutant. Catalysis Communications, 149, 106193 1-5 (2021).
  • Michael Kotík, Hana Javůrková, Katerina Brodsky, Helena Pelantová: Two fungal flavonoid-specific glucosidases/rutinosidases for rutin hydrolysis and rutinoside synthesis under homogeneous and heterogeneous reaction conditions. AMB Express, 11, 136: 1-11 (2021).
  • Katerina Brodsky, Michal Kutý, Helena Pelantová, Josef Cvačka, Martin Rebroš, Michael Kotík, Ivana Kutá Smatanová, Vladimír Křen, Pavla Bojarová: Dual Substrate Specificity of the Rutinosidase from Aspergillus niger and the Role of Its Substrate Tunnel. International Journal of Molecular Sciences, 21 (16), 5671: 1-21 (2020).

 

Last update: March 11, 2025