Molecular Nutrition & Food Research, 2400500 (1-14) (2024)

5 listopadu, 2024 12:58 pm Published by Leave your thoughts

IF 4,5

Mutual Interactions of Silymarin and Colon Microbiota in Healthy Young and Healthy Elder Subjects

Tomisová Kateřina, Jarošová Veronika, Maršík Petr, Bergo Mascellani Anna, Cinek Ondřej, Hlináková Lucie, Klouček Pavel, Janoušek Václav, Valentová Kateřina, Havlík Jaroslav

 Abstract

This multi-omic study investigates the bidirectional interactions between gut microbiota and silymarin metabolism, highlighting the differential effects across various age groups. Silymarin, the extract from Silybum marianum (milk thistle), is commonly used for its hepatoprotective effects.

This study provides insights into microbiome functionality in metabolizing dietary flavonolignans, highlighting implications for age-specific nutritional strategies, and advancing our understanding of dietary (poly)phenol metabolism.

 

 

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