2023 Publications

  • Lactose-Functionalized Carbosilane Glycodendrimers Are Highly Potent Multivalent Ligands for Galectin‑9 Binding: Increased Glycan Affinity to Galectins Correlates with Aggregation Behavior

Monika Müllerová, Michaela Hovorková, Táňa Závodná, Lucie Červenková Šťastná, Alena Krupková, Vojtěch Hamala, Kateřina Nováková, Jan Topinka, Pavla Bojarová, Tomáš Strašák

Biomacromolecules, 24, 11, 4705-4717     PDF

  • Flavonoids as Aglycones in Retaining Glycosidase-Catalyzed Reactions: Prospects for Green Chemistry

Michael Kotík, Natalia Kulik, Kateřina Valentová

Journal of Agricultural and Food Chemistry, 71, 41, 14890-14910     PDF

  • Inhibition of xanthine oxidase-catalyzed xanthine and 6-mercaptopurine oxidation by luteolin, naringenin, myricetin, ampelopsin and their conjugated metabolites

Orsolya Balázs, Ágnes Dombi, Balázs Z. Zsidó, Csaba Hetényi, Kateřina Valentová, Róbert G. Vida, Miklós Poór

Biomedicine & Pharmacotherapy, 167, November 2023, 115548, 1-10     PDF

  • Galectin-targeting glycocalix[4]arenes can enter the cells†

Miluše Vlachová, Van Nguyen Tran, Jakub Červený, František Dolníček, Lucie Petrásková, Helena Pelantová, Ondřej Kundrát, Josef Cvačka, Zuzana Bosáková, Vladimír Křen, Pavel Lhoták, Jitka Viktorová, Pavla Bojarová

Chemical Communications, 59, 10404-10407

  • Highly functionalized diaminocyclopentanes: A new route to potent and selective inhibitors of human O-GlcNAcase

Patrick Weber, Zuzana Mészáros, Pavla Bojarová, Manuel Ebner, Roland Fischer, Vladimír  Křen, Natalia Kulik, Philipp Müller, Miluše Vlachová, Kristýna Slámová, Arnold E. Stütz, Martin Thonhofer, Ana Torvisco, Tanja M. Wrodnigg, Andreas Wolfsgruber

Bioorganic Chemistry, 140, November 2023, 106819, 1-14

  • Rutinosidase and other diglycosidases: Rising stars in biotechnology

Vladimír Křen, Pavla Bojarová

Biotechnology Advances, 68, November 2023, 108217, 1-20

  • Combination of plant phenolics and isoquinolinium alkaloids protects gingival fibroblast and improves post-extraction healing after lower third molar extraction

Karin Chytilová, Adéla Galandáková, Kateřina Valentová, Peter Tvrdý

Biomedical Papers, 167, 2, 131-138     PDF

  • Oligosaccharide Ligands of Galectin-4 and Its Subunits: Multivalency Scores Highly

Kristýna Slámová, Jakub Červený, Zuzana Mészáros, Tereza Friede, David Vrbata, Vladimír Křen, Pavla Bojarová

Molecules, 28, 10, 4039, 1-15     PDF 

  • Advanced high-affinity glycoconjugate ligands of galectins

Michaela Hovorková, Jakub Červený, Ladislav Bumba, Helena Pelantová, Josef Cvačka, Vladimír Křen, Olivier Renaudet, David Goyard, Pavla Bojarová

Bioorganic Chemistry, 131, February 2023, 106279, 1-12     PDF

  • Biotransformation of Natural Products and Phytochemicals: Metabolites, Their Preparation and Properties – Editorial

Kateřina Valentová

International Journal of Molecular Sciences, 24, 9, 8030, 1-3     PDF

  • Bio-Based Valorization of Lignin-Derived Phenolic Compounds: A Review

Ludmila Martínková, Michal Grulich, Miroslav Pátek, Barbora Křístková, Margit Winkler

Biomolecules, 13, 5, 717, 1-25     PDF

  • Recent Progress in the Production of Cyanide-Converting Nitrilases—Comparison with Nitrile-Hydrolyzing Enzymes

Ludmila Martínková, Natalia Kulik, Anastasia Sedova, Barbora Křístková, Pavla Bojarová

Catalysts, 13, 3, 500, 1-19     PDF

  • Hesperidin, Hesperetin, Rutinose, and Rhamnose Act as Skin Anti-Aging Agents

Renáta Novotná, Denisa Škařupová, Jiří Hanyk, Jitka Ulrichová, Vladimír Křen, Pavla Bojarová, Katerina Brodsky, Jitka Vostálová, Jana Franková

Molecules, 28, 4, 1728, 1-14     PDF

  • Glycocalix[4]arenes and their affinity to a library of galectins: the linker matters

Dorota Konvalinková, František Dolníček, Michaela Hovorková, Jakub Červený, Ondřej Kundrát, Helena Pelantová, Lucie Petrásková, Josef Cvačka, Margarita Faizulina, Beena Varghese, Petr Kovaříček, Vladimír Křen, Pavel Lhoták, Pavla Bojarová

Organic & Biomolecular Chemistry, 21, 6, 1294-1302     PDF

  • Organic Acid to Nitrile: A Chemoenzymatic Three-Step Route

Winkler Margit, Horvat Melissa, Schiefer Astrid, Weilch Victoria, Rudroff Florian, Pátek Miroslav, Martínková Ludmila

Advanced Synthesis & Catalysis, 365, 1, 37-42     PDF

  • Recent trends in the treatment of cyanide-containing effluents: Comparison of different approaches

Ludmila Martínková, Pavla Bojarová, Anastasia Sedova, Vladimír Křen

Critical Reviews in Environmental Science and Technology, 53, 3, 416-434     PDF

  • Scanning aldoxime dehydratase sequence space and characterization of a new aldoxime dehydratase from Fusarium Vanettenii

Barbora Křístková, Robert Rädisch, Natalia Kulik, Melissa Horvat, Lenka Rucká, Milan Grulich, Florian Rudroff, Alan Kádek, Miroslav Pátek, Margit Winkler, Ludmila Martínková

Enzyme and Microbial Technology, 164, 110187, 1-13     PDF

  • Metabolic profiling of silymarin constituents in urine and feces of healthy volunteers: A 90-day study

Kateřina Lněničková, Jiří Vrba, Pavel Kosina, Barbora Papoušková, Chahrazed Mekadim, Jakub Mrázek, Milan Sova, Eliška Sovová, Kateřina Valentová, Vladimír Křen, Pavla Kouřilová, Jana Vrbková, Jitka Ulrichová

Journal of Functional Foods, 100, 105391, 1-16     PDF

  • Interaction of luteolin, naringenin, and their sulfate and glucuronide conjugates with human serum albumin, cytochrome P450 (CYP2C9, CYP2C19, and CYP3A4) enzymes and organic anion transporting polypeptide (OATP1B1 and OATP2B1) transporters

Hana Kaci, Slávka Bodnárová, Eszter Fliszár-Nyúl, Beáta Lemli, Helena Pelantová, Kateřina Valentová, Éva Bakos, Csilla Özvegy-Laczka, Miklós Poór

Biomedicine & Pharmacotherapy, 157, 114078, 1-12     PDF