2022 Publications

  • Sulfation of Phenolic Acids: Chemoenzymatic vs. Chemical Synthesis

Viola Kolaříková, Katerina Brodsky, Lucie Petrásková, Helena Pelantová, Josef Cvačka, Libor Havlíček, Vladimír Křen, Kateřina Valentová

International Journal of Molecular Sciences, 23, 23, 15171, 1-16     PDF

  • Selectively Halogenated Flavonolignans—Preparation and Antibacterial Activity

Martina Hurtová, Kristýna Káňová, Simona Dobiasová, Kateřina Holasová, Denisa Čáková, Lan Hoang, David Biedermann, Marek Kuzma, Josef Cvačka, Vladimír Křen, Jitka Viktorová, Kateřina Valentová

International Journal of Molecular Sciences, 23, 23, 15121, 1-18     PDF

  • Mutation Hotspot for Changing the Substrate Specificity of β-N-Acetylhexosaminidase: A Library of GlcNAcases

Pavlína Nekvasilová, Kulik Natalia, Michael Kotík, Lucie Petrásková, Kristýna Slámová, Vladimír Křen, Pavla Bojarová

Internationa Journal of Molecular Sciences, 20, 23, 12456, 1-17     PDF

  • Bacterial Aryl Sulfotransferases in Selective and Sustainable Sulfation of Biologically Active Compounds using Novel Sulfate Donors

Katerina Brodsky, Kristýna Káňová, Dorota Konvalinková, Kristýna Slámová, Helena Pelantová, Kateřina Valentová, Pavla Bojarová, Vladimír Křen, Lucie Petrásková

ChemSusChem, 15, 18, e202201253, 1-9     PDF

  • Diaminocyclopentane-derived O-GlcNAcase inhibitors for combating tau hyperphosphorylation in Alzheimer’s disease

Weber Patrick, Mészáros Zuzana, Jagečić Denis, Hribljan Valentina, Mitrečić Dinko, Bojarová Pavla,  Slámová Kristýna, Vrba Jiří, Kulik Natalia, Křen Vladimír, Stütz E. Arnold

Chemical Communications, 58, 63, 8838-8841     PDF

  • Carbohydrate-derived bicyclic selenazolines as new dual inhibitors (cholinesterases/OGA) against Alzheimer’s disease

Martha Velueta-Viveros, Macarena Martínez-Bailén, Adrián Puerta, Laura L. Romero-Hernández, Vladimír Křen, Penélope Merino-Montiel, Sara Montiel-Smith, Miguel X. Fernandes, Antonio J. Moreno-Vargas, José M. Padrón, Óscar López, José G. Fernández-Bolaños

Bioorganic Chemistry, 127, 105983, 1-13     PDF

  • Silybin and its congeners: from traditional medicine to molecular effects

Vladimír Křen, Kateřina Valentová

Natural Product Reports, 39, 6, 1264-1281     PDF

  • Hypertransglycosylating Variants of the GH20 ß-N-Acetylhexosaminidase for the Synthesis of Chitooligomers

Zuzana Mészáros, Lucie Petrásková, Natalia Kulik, Helena Pelantová, Pavla Bojarová, Vladimír Křen, Kristýna Slámová

Advanced Synthesis & Catalysis, 364, 12, 2009-2022     PDF

  • Stability and ultraviolet A photostability of silymarin polyphenols and its consequences for practical use in dermatology

Pavel Kosina, Alena Ryšavá, Jitka Vostálová, Barbora Papoušková, David Biedermann, Jitka Ulrichová, Alena Rajnochová Svobodová

Journal of  Photochemistry & Photobiology, A: Chemistry, 429, 113897, 1-12     PDF

  • Recent trends in the treatment of cyanide-containing effluents: Comparison of different approaches

Ludmila Martínková, Pavla Bojarová, Anastasia Sedova, Vladimír Křen

Critical Reviews in Environmental Science and Technology

  • Interaction of Flavonoids with Zinc and Zinc-Containing Enzymes

Marcel Hrubša, Václav Tvrdý, Michal Kutý, Kateřina Valentová, Vladimír Křen, Přemysl Mladěnka

Journal of Agricultural and Food Chemistry, 70, 20, 6134-6144     PDF

  • Sulfated Phenolic Substances: Preparation and Optimized HPLC Analysis

Lucie Petrásková, Kristýna Káňová, Katerina Brodsky, Anastasiia Hetman, Barbora Petránková, Helena Pelantová, Vladimír Křen, Kateřina Valentová

International Journal of Molecular Sciences, 23, 10, 5743, 1-18     PDF

  • Methods of in vitro study of galectin-glycomaterial interaction

Viktoria Heine, Carina Dey, Pavla Bojarová, Vladimír Křen, Lothar Elling

Biotechnology Advances, 58, 107928, 1-23     PDF

  • Targeted Fucosylation of Glycans with Engineered Bacterial Fucosyltransferase Variants

Viktoria Heine, Helena Pelantová, Pavla Bojarová, Vladimír Křen, Lothar Elling

ChemCatChem, 14, 6, e202200037, 1-9     PDF

  • Engineered Glycosidases for the Synthesis of Analogs of Human Milk Oligosaccharides

Pavlína Nekvasilová, Michaela Hovorková, Zuzana Mészáros, Lucie Petrásková, Helena Pelantová, Vladimír Křen, Kristýna Slámová, Pavla Bojarová

International Journal of Molecular Sciences, 23, 8, 4106, 1-13     PDF

  • Laccases and Tyrosinases in Organic Synthesis

Ludmila Martínková, Barbora Křístková, Vladimír Křen 

International Journal of Molecular Sciences, 23, 7, 3462, 1-19     PDF

  • A Career in Biocatalysis: Kurt Faber

Vladimír Křen, Wolfgang Kroutil, Mélanie Hall

ACS Catalysis, 12, 7, 3909-3922     PDF

  • Flavonolignans from silymarin modulate antibiotic resistance and virulence in Staphylococcus aureus

Kateřina Holasová, Bára Křížskovská, Lan Hoang, Simona Dobiasová, Jan Lipov, Tomáš Macek, Vladimír Křen, Kateřina Valentová, Tomáš Ruml, Jitka Viktorová

Biomedicine & Pharmacoteraphy, 149, 112806, 1-14     PDF

  • Glycopolymers Decorated with 3‑O-Substituted Thiodigalactosides as Potent Multivalent Inhibitors of Galectin‑3

Vrbata David, Filipová Marcela, Tavares R. Marina, Červený Jakub, Vlachová Miluše, Šírová Milada, Pelantová Helena, Petrásková Lucie, Bumba Ladislav, Konefal Rafal, Etrych Tomáš, Křen Vladimír, Chytil Petr, Bojarová Pavla

Journal of medicinal Chemistry, 65, 5, 3866-3878     PDF

  • Metabolism of Aldoximes and Nitriles in Plant‐Associated Bacteria and Its Potential in Plant–Bacteria Interactions

Robert Rädisch, Miroslav Pátek, Barbora Křístková, Margit Winkler, Vladimír Křen, Ludmila Martínková 

Microorganisms, 10, 3, 549, 1-16     PDF

  • Discovery of human hexosaminidase inhibitors by in situ screening of a library of mono- and divalent pyrrolidine iminosugars

Pingitore Valeria, Martínez-Bailén Macarena, Carmona T. Ana, Mészáros Zuzana, Kulik Natalia, Slámová Kristýna, Křen Vladimír, Bojarová Pavla, Robina Inmaculada, Moreno-Vargas J. Antonio

Bioorganic Chemistry, 120, 105650, 1-12     PDF

  • Preparation of Synthetic and Natural Derivatives of Flavonoids Using Suzuki–Miyaura Cross-Coupling Reaction

Martina Hurtová, David Biedermann, Zuzana Osifová, Josef Cvačka, Kateřina Valentová, Vladimír Křen 

Molecules, 27, 3, 967, 1-16     PDF

  • Chemoenzymatic one-pot reaction from carboxylic acid to nitrile via oxime†

Melissa Horvat, Victoria Weilch, Robert Rädisch, Sebastian Hecko, Astrid Schiefer, Florian Rudroff, Birgit Wilding, Norbert Klempier, Miroslav Pátek, Ludmila Martínková, Margit Winkler

Catalysis Science & Technology, 12,1,62-66     PDF

  • 2-Acetamido-2-deoxy-D-glucono-1,5-lactone Sulfonylhydrazones: Synthesis and Evaluation as Inhibitors of Human OGA and HexB Enzymes

Mariann Kiss, István Timári, Teréz Barna, Zuzana Mészáros, Kristýna Slámová, Pavla Bojarová, Vladimír Křen, Joseph M. Hayes, László Somsák

International Journal of Molecular Sciences, 23, 3, 1037, 1-19     PDF