Haloalkane dehalogenases (HLDs) catalyze the hydrolytic dehalogenation in a wide range of halogenated compounds, yielding an alcohol, a proton and a halide. They play an important role in the detoxification of a wide range of halogenated pollutants. HLDs have attracted the interest of biotechnological companiesand the chemical industry as valuable biocatalysts for bioremediation and biotransformation reactions.
Further reading
- Kotik M, Davidová A, Voříšková J, Baldrian P. Bacterial communities in tetrachloroethene-polluted groundwaters: a case study. Science of the Total Environment, 454−455 (2013) 517−527.
- Kotik M, Faměrová V. Sequence diversity in haloalkane dehalogenases, as revealed by PCR using family-specific primers. Journal of Microbiological Methods, 88 (2012) 212−217.
Doc. Ing. Kateřina Valentová, PhD.